Ultherapy PRIME®

Ultherapy PRIME is made by Merz Aesthetics and is the current generation of Ultherapy, a non-surgical treatment that uses focused sound waves (ultrasound), rather than a laser or a needle, to gently warm a layer of tissue beneath the surface of the skin; Merz states that controlled warmth is intended to stimulate the body's own production of collagen over time. What sets this device apart from many other ultrasound-based machines is that the provider can see an image of the layers beneath the skin on a screen while treating, so the energy can be aimed at a specific depth rather than applied blind; Merz describes that pairing of real-time visualization with non-invasive ultrasound lifting as what sets the device apart from other ultrasound systems. Ultherapy originally received FDA clearance (via the De Novo pathway) for a non-invasive brow lift in September 2009, followed by clearance for the neck and under-chin area in 2012, for ultrasound visualization of tissue layers in 2013, and for improving lines and wrinkles on the décolleté (upper chest) in 2014. Merz Aesthetics launched the newer "Ultherapy PRIME" platform on September 23, 2024, describing it as delivering a clearer real-time image on screen and a faster treatment session compared with the earlier-generation system; Merz has since announced additional FDA clearances extending Ultherapy PRIME to skin laxity on the arms and abdomen (November 5, 2025) and, most recently, the knees (August 11, 2026). Merz describes results as developing gradually over the weeks following treatment as the body's own collagen response continues, rather than appearing immediately.